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BURNOUT™ Packaging

Burnout™

Stimulates adrenal function for use in exhaustion and adrenal burnout. Years of stress can exhaust the adrenal glands which the body relies on to manufacture the stress-coping and anti-fatigue hormone, cortisol. The adrenals also produce aldosterone, essential for water/mineral balance, as well as pregnenolone and DHEA, the building blocks of estrogen, progesterone and testosterone. Burnout™ is indicated for people who are suffering from adrenal exhaustion from years of exposure to stress, and works by boosting excessively low levels of cortisol. Adrenal fatigue is characterised by tiredness and chronic fatigue, coupled with some of the following symptoms: chronic pain, mild depression, anxiety, reduced stress-coping ability, patchy hair loss, insomnia, poor blood sugar control (up or down), weight gain, frequent infections, reduced sex drive, a craving for fatty, salty or high-protein foods, difficulty getting up in the morning, worsening of allergies, reduced memory and focus, alternating diarrhoea and constipation, and indigestion. Burnout™ contains concentrated herbal extracts for enhanced effectiveness, not herb powder and has synergistic dual action: stimulating adrenal function and reducing adrenal hormone breakdown.

R242.00

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Product Indications

Long term stress may exhaust the adrenal glands which the body relies on to manufacture the stress-coping and anti-fatigue hormone, cortisol. Burnout™ is indicated for people who are suffering from exhaustion bought on by long-term exposure to stress, and works by nourishing the adrenal glands and supporting healthy blood sugar metabolism. Adaptogenic herbs and other nutrients support the hypothalamus-pituitary-adrenal (HPA) axis, the part of the neuroendocrine system that manages the stress response.

Product Composition

Each capsule contains the following as active ingredients:

Panax Ginseng (Korean) 5:1 Extract 100mg
Liquorice 6:1 Extract 250mg
Echinacea Extract 100mg
Chromium polynicotinate 100µg
Vitamin B1 (thiamine pyrophosphate) 3.1mg
Vitamin B5 (calcium-d-pantothenate) 25mg

Adrenal Chromium Complex™ (a proprietary complex of chromium polynicotinate, Vitamin B1, Vitamin B5) Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), microcrystalline cellulose, magnesium stearate (vegetarian – flow agent), magnesium silicate, silicon dioxide and colloidal silicon dioxide. Contains no colourants, preservatives, lactose, gluten, yeast, starch or artificial fillers. Contains plant extracts and natural fillers, with no colourants added – therefore the colour of the capsule contents may vary slightly from batch to batch.

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action

Ginseng is commonly classed as one of a group of herbs with adaptogenic properties. There is some evidence that it might work against stress by affecting the hypothalamic-pituitary-adrenal (HPA) axis. Panax ginseng saponins seem to increase serum cortisol concentrations. Glycyrrhetinic acid from liquorice inhibits renal 11-beta-hydroxysteroid dehydrogenase, reducing conversion of cortisol to inactive cortisone in the kidneys. Some research shows that Panax ginseng appears to support liquorice by increasing serum cortisol concentrations. Research suggests that Echinacea is useful for boosting the immune system, possibly by inducing macrophages to produce cytokines and by increasing phagocytosis. Chromium plays a role in blood sugar control in the body. One proposed mechanism is by the potentiation of insulin activity to normalize insulin function. Pantothenic acid is a precursor of coenzyme A, which is required in the acetylation reactions in gluconeogenesis; in the release of energy from carbohydrates; in the synthesis and degradation of fatty acids; and in the synthesis of sterols, steroid hormones, acetylcholine, and other compounds. Vitamin B1 roles include regulation of neurotransmitters and thereby supports cognitive function and memory.

Dosage Directions

Adult and children over 12 years dosage: Take 1 capsule twice daily, preferably with a meal. This product should be taken continuously for six weeks, followed by a two week break. The reason for the break is that Korean ginseng, liquorice and echinacea stop working if taken continuously. This dosage regimen should be continued for approximately two years, or until full energy levels and stress coping ability return to normal. It may take from a few weeks, to three months, for the effects of BURNOUT™ to begin to become apparent.

Product Warnings

Do not exceed recommended dosages unless on the advice of a healthcare provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Safety in children has not been established.

Side Effects

Side effects may include insomnia, diarrhoea, vomiting, headache, heartburn, allergy, constipation, mastalgia, vaginal bleeding, amenorrhea, tachycardia, palpitations, hypertension, hypotension, oedema, decreased appetite, hyperpyrexia, pruritus, rose spots, headache, vertigo, euphoria and mania.

Contraindications

Anticoagulant/ antiplatelet drugs: Liquorice seems to increase the metabolism and decrease levels of warfarin. Individuals taking warfarin should avoid liquorice.

Product Interactions

Anticoagulant/ antiplatelet drugs: Liquorice seems to increase the metabolism and decrease levels of warfarin. Individuals taking warfarin should avoid Burnout™.

Alcohol: Significantly increases the clearance of alcohol.

Anti-diabetic drugs: May enhance the blood glucose lowering effects, use with caution.

Caffiene: Theoretically caffiene may have an additive effect to the stimulant effects of Panax ginseng.

Cytochrome P450 2D6, P450 2C9 P 450 3A4 and P450 2B6: There is some evidence that Panax Ginseng and liquorice can inhibit these cytochromes. Caution should be exercised when using drugs metabolised by this enzyme. Some of these drugs include: amitriptyline, clozapine, codeine, desipramine, donepezil, fentanyl, flecainide, fluoxetine, meperidine, methadone, metoprolol, olanzapine, ondansetron, tramadol, trazodone, ketamine, phenobarbital, orphenadrine , secobarbital, dexamethasone, celecoxib, diclofenac, fluvastatin, glipizide, ibuprofen, losartan , phenytoin, piroxicam, tamoxifen, tolbutamide, torsemide, warfarin, lovastatin, clarithromycin, cyclosporine, diltiazem, estrogens, indinavir, triazolam and others.

Antihypertensive drugs: Liquorice increases blood pressure in a dose dependant manner.

Digoxin: Overuse and misuse of liquorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Cortisone: Use of cortisone with this product could cause excessive potassium depletion and require potassium supplementation, speak to your medical practitioner.

Special Precautions

Do not use this product if you suffer from the following conditions: congestive heart failure, heart arrhythmias, severe kidney disease, jaundice or cirrhosis of the liver, unless under the supervision of a medical practitioner.

Liquorice and ginseng can raise blood pressure, do not use if you have high blood pressure.

Pregnancy & Breastfeeding

Safety in pregnancy and breastfeeding has not been established.

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