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Calcium Glycinate & Vitamin D3 Packaging

Calcium Glycinate

Calcium is one of the most important minerals and is essential for building and maintaining healthy bones. Calcium is also essential for proper functioning of the brain, heart and muscles. Calcium plays an important role in lowering blood pressure, cholesterol, fat absorption, gum disease and insomnia. Women lose an average of 15% of their bone mass during menopause, therefore calcium supplementation is essential. Calcium glycinate is the most bioavailable and most soluble form of supplemental calcium. It is 180% better absorbed than calcium citrate and 21% better absorbed than calcium citrate-malate. Vitamin D3 is required for optimal absorption of calcium. Boron plays an important role in mineral metabolism, by preventing calcium loss and bone demineralisation.

R236.00

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Product Indications

Calcium is an essential mineral for building and maintaining healthy bones and teeth. Adequate calcium as part of a healthy diet and physical activity may reduce the risk of osteoporosis in later life. Women lose a large percentage of their bone mass during menopause, therefore adequate calcium intake is essential. Calcium glycinate is the most bioavailable and soluble form of supplemental calcium. Vitamin D3 is required for optimal absorption of calcium. Boron plays an important role in mineral metabolism, thereby reducing calcium loss.

Product Composition

Each tablet contains the following as active ingredients:

Calcium glycinate
(which supplies 150mg bioavailable elemental calcium)
750mg
Vitamin D3 200IU
Boron 500µg

Inactive ingredients: Microcrystalline cellulose, isomalt, magnesium stearate (vegetarian-flow agent), magnesium silicate, copovidone.

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action

The bone and teeth account for 99% of the calcium in the body in the form of hydroxyapatite. Calcium is also present in blood, extracellular fluid, muscle, and other tissues. It is essential for nerve transmission, muscle contraction, vascular contraction, vasodilation, glandular secretion, cell membrane and capillary permeability, enzyme reactions, respiration, renal function, and blood coagulation. It also plays a role in neurotransmitter and hormone release and storage, uptake and binding of amino acids, cyanocobalamin (vitamin B12) absorption, and gastrin secretion. Calcium in bone is a reserve source of calcium that can be mobilized to maintain extracellular calcium concentrations. Vitamin D enhances the efficiency of the intestinal absorption of calcium, primarily in the duodenum and jejunum, and phosphorus, particularly in the jejunum and ileum. Boron is believed to play a role in mineral metabolism, with effects on calcium, phosphorus and vitamin D.

Dosage Directions

Adults and children over 8 years of age: Take 1 tablet twice daily, or 2 tablets once daily (preferably after breakfast), or as recommended by your health care provider.

Children 4-8 years of age: Take 1 tablet once daily, or as recommended by your health care provider.

Calcium should be consumed with meals in order to be absorbed more effectively.

Product Warnings

Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Side Effects

Side effects may include mild diarrhoea, constipation, headache, burping and flatulence.

Contraindications

There are no known contraindications.

Product Interactions

The use of Vitamin D3 together with the following products may result in adverse effects, and concomitant use should be avoided: Calcipotriene, digoxin, diltiazem, thiazide diuretics, verapamil and aluminium containing products in patients with renal impairment.

Biphosphonates: Calcium can decrease the absorption of biphosphonates. Doses of biphosphonates should be betaken at least 30-minutes before calcium, but preferably at a different time of the day.

Quinolone antibiotics: Calcium can form insoluble complex’s with these antibiotics leading to reduced absorption. Patients should take these drugs at least two hours before or four to six hours after magnesium.

Tetracycline antibiotics: Magnesium and calcium can form insoluble complex’s with these antibiotics leading to reduced absorption. Patients should take these drugs at least two hours before or four to six hours after magnesium.

Calcipotriene: When taken in combination with calcium it can increase the risk of hypercalcaemia.

Digoxin: Hypercalcaemia can increases the risk of fatal cardiac arrhythmias.

Diltiazem and verapamil: Hypercalcaemia reduces their effectiveness in atrial fibrillation.

Estrogens: Concomitant administration may increase estrogen levels.

Levothyroxine: Calcium reduces levothyroxine absorption and they should be taken at least four hours apart.

Sotalol: Calcium reduces sotalol absorption and the combination should be taken at least four to six hours apart.

Thiazides: Thiazides reduce calcium excretion by the kidneys. Taking high doses of calcium with thiazides increases the risk of milk-alkali syndrome.

Pregnancy & Breastfeeding

Safe for use during pregnancy and breastfeeding.

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