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Herbal Sleep Packaging

Herbal Sleep™

A blend of three safe, non-addictive and effective herbal extracts (Valerian, Passion Flower and Corydalis) to hasten the onset of sleep, assist with insomnia and improve quality of sleep. Valerian is a root extract that induces sleep and improves quality of sleep. It also reduces the break-down of the brain’s natural sleep-inducing neurotransmitter, GABA. Corydalis is a herb that promotes calmness and relieves anxiety. Passion Flower calms the central nervous system.

R215.00

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Product Indications

Valerian is a root extract that induces sleep and improves quality of sleep. It also reduces the break-down of the brain’s natural sleep-inducing neurotransmitter, GABA. Corydalis is a herb that promotes calm and relieves anxiety. Passion flower calms the central nervous system.

Product Composition

Each dose (2 capsules) contains the following as active ingredients:

Valerian 5:1 extract 350mg
Corydalis 10:1 extract 400mg
Passion flower 10:1 extract 200mg

Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), micro-crystalline cellulose, magnesium stearate (vegetarian – flow agent), magnesium silicate, silicon dioxide and colloidal silicon dioxide. Contains plant extracts and natural fillers, with no colourants added – therefore the colour of the capsule contents may vary slightly from batch to batch.

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action

The pharmacological effects of valerian have primarily been attributed to valepotriades. The sesquiterpenes, valerenic acid and kessel glycol, have been shown to cause sedation in animals. Valerenic acid and other constituents of valerian are gamma-aminobutyric acid (GABA) agonists. Valerian constituents may inhibit the enzyme system responsible for the central catabolism of GABA, increasing GABA concentrations and decreasing central nervous system (CNS) activity. Valerian may also bind directly to GABA-A receptors and stimulate the release and reuptake of GABA. Valerian might also affect sleep regulation with activity on adenosine and 5-hydroxytryptamine-1. A naturally occuring alkaloid, dl-Tetrahydropalmatine (dl-THP), present in Corydalis, has been intensively studied for its sedative and hypnotic effects. It is believed the mechanism and target of action involves the dopaminergic neurotransmission system. Some evidence suggests that the passionflower constituent apigenin binds to central benzodiazepine receptors, possibly causing anti-anxiolytic effects without impairing memory or motor skills.

Dosage Directions

Adults and children over 12 years of age: Take 2 capsules approximately one hour before bedtime.

Can be taken with a meal or on an empty stomach.

Not intended for use in children under 12 years of age.

The dosage can be increased up to a maximum of 4 capsules, but only under the supervision of a health care provider.

Product Warnings

Do not exceed recommended dosages unless on the advice of a health care provider.

Do not use this product if you are allergic to any of the ingredients.

If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Safety in children has not been established.

Side Effects

Side effects may include dizziness, confusion, sedation, headache and ataxia.

Contraindications

Do not use Herbal Sleep™ if you have a history of kidney or liver disease.

Product Interactions

CNS Depressants: Concomitant use with sedatives might increase the risk of excessive sedation and drowsiness. Some CNS depressants are benzodiazepines, pentobarbital, phenobarbital, secobarbital, thiopental, fentanyl, morphine, propofol and others.

Special Precautions

Do not drive or operate machinery for 8 hours after taking Herbal Sleep™.

Alcohol can compound the drowsiness caused by Herbal Sleep™ and should be used with caution.

Surgery: The sedative effect of Herbal Sleep™ might cause additive CNS depression when combined with anaesthesia during surgical procedures.

Discontinue Herbal Sleep™ at least 2 weeks before elective surgical procedures.

Pregnancy & Breastfeeding

Not to be taken while pregnant or breastfeeding.

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