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Sleep Naturally Packaging

Sleep Naturally™

Combines three natural ingredients that work to promote deeper sleep, faster, without the “morning hangover” effect associated with prescription or over the counter sleep medication. Glycine, an amino acid, has a calming effect on the brain and research indicates individuals reach deep states of sleep faster with glycine. Another amino acid, theanine, has historically been used for its relaxing and anti-anxiety effects. These effects are believed to be due to increased levels of GABA in the body, which plays an important role in sleep. Magnesium helps relax muscles and is believed to block the release of excess excitatory neurotransmitters in the brain.

R236.00

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Product Indications

A glycine amino acid rich drink which promotes improved sleep by reducing the anxiety associated with sleeplessness.

Product Composition

Each sachet contains the following as active ingredients:

Glycine 3000mg
Theanine 300mg
Magnesium 200mg

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action

Glycine, an amino acid, acts as an agonist of the glutamate receptor N-methyl-D-aspartate (NMDA). Another amino acid, theanine has historically been used for its relaxing and anti-anxiety effects. Theanine decreases norepinephrine in animal studies which may partly explain its anti-anxiety effect. Magnesium helps relax muscles and is believed to block the release of excess excitatory neurotransmitters in the brain.

Dosage Directions

Adults: Dissolve 1 sachet into approximately 100ml water at bed-time. Consume within 24 hours of mixing. This drink is sugar-free and will not promote dental caries. You do not have to brush your teeth after drinking.

Product Warnings

Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before start taking any new medicine, supplement or remedy. Safety in children has not been established.

Side Effects

Side effects may include nausea, vomiting, diarrhoea, upper gastrointestinal tract discomfort and drowsiness.

Contraindications

There are no known contraindications.

Product Interactions

Antihypertensive medicines: Theoretically, concomitant use of theanine might potentiate the activity of antihypertensive medication.

Bisphosphonates: Magnesium can decrease bisphosphonate absorption. Individuals should separate doses of magnesium and these doses by at least 2 hours.

Calcium channel blockers: Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers.

Clozapine: Glycine can worsen symptoms when given with clozapine in individuals suffering with schizophrenia.

Potassium sparing diuretics: They also have magnesium sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Quinolone antibiotics: Magnesium can decrease quinolone absorption. Individuals should take magnesium at least 2 hours before, or 4 hours after quinolone antibiotics.

Stimulant medicines: Theoretically, theanine may decrease the effects of stimulant medicines such as caffeine.

Tetracycline antibiotics: Magnesium can decrease tetracycline antibiotic absorption. Individuals should take magnesium at least 2 hours before, or 4 hours after tetracycline antibiotics.

Pregnancy & Breastfeeding

Safety during pregnancy and breastfeeding has not been established.

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