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Bio CalMag (Calcium & Magnesium) Packaging

Bio-CalMag™

Calcium and magnesium are essential minerals for healthy bones and muscles. They also help protect the functioning of the nervous system and heart. Bio-CalMag contains the most effective forms of calcium and magnesium known as glycinate amino acid chelates. Glycinates are best absorbed and will also not neutralise stomach acid, unlike most calcium containing products. Neutralising germ-killing stomach acid can result in infections in the intestine and body. Bio-CalMag contains the ideal ratio of 1 part magnesium: 2 parts calcium. Calcium glycinate is 1.8 times (180%) better absorbed than calcium citrate and is 21% better absorbed than calcium citrate-malate. It is 205 times more soluble than calcium carbonate. With added vitamin D3 for optimal calcium absorbtion. Boron plays an important role in mineral metabolism, by preventing calcium loss and bone demineralisation.

R303.00

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Product Indications

Calcium and magnesium are essential minerals for healthy bones and muscles. They also help protect the functioning of the nervous system and heart. Bio-Calmag contains the most effective forms of calcium and magnesium known as amino acid chelates. Glycinates have the best absorption rates and will not neutralise stomach acids, as seen with most calcium containing products. Neutralising germ-killing stomach acid can result in infections developing in the intestine and body. Lowered stomach acid also leads to decreased absorption of many other important nutrients in the diet. Bio-Calmag contains the ideal ratio of 1 part magnesium to 2 parts calcium. Calcium glycinate is 1.8 times (180%) better absorbed than calcium citrate and is 21% better absorbed than calcium citrate-malate. It is 205 times more soluble than calcium carbonate.

Product Composition

Each tablet contains the following as active ingredients:

Calcium glycinate, (standardised to 19,3% Calcium)
Supplying 100mg absorbable calcium
517.5mg
Magnesium glycinate, (standardised to 18% Magnesium)
Supplying 50mg absorbable magnesium
277.5mg
Vitamin D3 100IU
Boron 250µg

Inactives: Microcrystalline cellulose, isomalt, magnesium stearate (vegetarian-flow agent), magnesium silicate, and silicon dioxide.

Storage Instructions

Store in a cool dry place below 25ºC. Keep out of the reach of children.

Pharmacological Action

The bones and teeth contain more than 99% of the calcium in the human body. Calcium is also present in the blood, extracellular fluid, muscle and other tissues. Calcium is essential for nerve transmission, muscle contraction, vascular contraction, vasodilation, glandular secretion, cell membrane and capillary permeability, enzyme reactions, respiration, renal function, and blood coagulation. It also plays a role in neurotransmitter and hormone release and storage, uptake and binding of amino acids, cyanocobalamin (vitamin B12) absorption, and gastrin secretion. Magnesium is important for normal bone structure, and plays an essential role in more than 300 cellular reactions. Magnesium is required for the formation of cyclic AMP (cAMP) and is involved in ion movements across cell membranes. It is involved in protein synthesis and carbohydrate metabolism. Extracellular magnesium is critical to both maintaining nerve and muscle electrical potentials and transmitting impulses across neuromuscular junctions. Cardiac function is strongly influenced by electrolyte concentrations and some cardiac arrhythmias may be associated with magnesium deficiency.

Dosage Directions

Adults and children over 12 years of age: Take 2 tablets twice daily.

Children under 12 years of age: Take 2 tablets once daily.

Can be taken with or without meals.

Product Warnings

Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Side Effects

Side effects may include mild diarrhoea and flatulence.

Contraindications

Do not exceed recommended dosages unless on the advice of a health care provider.

Do not use this product if you are allergic to any of the ingredients.

If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Product Interactions

Vitamin D: Vitamin D assists in the absorption of magnesium. Low levels of Vitamin D may thus lead to reduced absorption of magnesium.

Biphosphonates: Magnesium and calcium can decrease the absorption of biphosphonates. Doses of magnesium and calcium and biphosphonates should be separated by at least 2 hours.

Calcium channel blockers: Magnesium could have an additive effect. Use with caution especially if taking high doses of magnesium.

Potassium sparing diuretics: These diuretics are also magnesium sparing and can potentially lead to increased magnesium levels with concomitant supplementation.

Quinolone antibiotics: Magnesium and calcium can form insoluble complexes with these antibiotics leading to reduced absorption. Individuals should take these medications at least two hours before or four hours after magnesium.

Tetracycline antibiotics: Magnesium and calcium can form insoluble complexes with these antibiotics leading to reduced absorption. Individuals should take this medication at least two hours before or four hours after magnesium.

Beta-agonists (albuterol or terbutaline): Beta-agonists promote the movement of magnesium from the extracellular to the intracellular space, and increase the excretion of magnesium in the urine.

Corticosteroids: Corticosteroids increase urinary magnesium excretion.

Calcipotriene: In combination with calcium it can increase the risk of hypercalcaemia.

Digoxin: Hypercalcaemia can increases the risk of fatal cardiac arrhythmias.

Diltiazem and verapamil: Hypercalcaemia reduces their effectiveness in atrial fibrillation.

Levothyroxine: Calcium reduces levothyroxine absorption and they should be taken at least four hours apart.

Sotalol: Calcium reduces sotalol absorption and the combination should be taken at least four hours apart.

Thiazides: Thiazides reduce calcium excretion by the kidneys. Taking high doses of calcium with thiazides increases the risk of milk-alkali syndrome.

Medications that reduce calcium in the body include: aluminium salts, antiepileptics, cholestyramine, corticosteroids, loop diuretics, mineral oil, proton pump inhibitors, stimulant laxatives, high caffeine intake.

Pregnancy & Breastfeeding

Safe for use in pregnancy and breastfeeding.

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