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Chromium Polynicotinate Packaging

Chromium Polynicotinate

The safest and best absorbed form available (better absorbed than chromium picolinate). Chromium enhances insulin receptor sensitivity and is useful for obesity, diabetes, insulin resistance (hyperinsulinaemia/glucose intolerance) and post-meal fatigue. Chromium may also help reduce carbohydrate cravings

R77.00

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Product Indications

Chromium is an essential trace mineral that potentiates insulin action and thus influences carbohydrate, protein, and fat metabolism. Chromium polynicotinate is a superior bioavailable and absorbable form of chromium.

Product Composition

Each tablet contains the following as active ingredients:

Chromium polynicotinate         200µg

Inactive ingredients: micro crystalline cellulose, vinylpyrrolidone-vinyl acetate, colloidal silicon dioxide, magnesium stearate.

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action

Chromium is thought to be the active component of glucose tolerance factor (GTF) which is a complex of molecules found in the body. The exact mechanism of action of chromium remains unclear. Chromium may act by potentiation of insulin activity to normalise insulin function. It may directly bind insulin, increase insulin binding to red blood cells, increase insulin receptor number or affect receptor proteins, increase insulin internalisation in cells, or increase pancreatic beta-cell glucose sensitivity. Chromium seems to play a role in the metabolism of both carbohydrates and fats.

Dosage Directions

Adults and children over 12 years of age: Take 1 tablet twice daily with meals, or as recommended by your health care provider. This dose can be doubled after 1-2 months if required.

Children 7-12 years of age: Take 1 tablet daily with a meal, or as recommended by your health care provider.

Product Warnings

Dose exceeding the recommended dosage can cause anaemia and liver dysfunction.

Do not exceed recommended dosages unless on the advice of a healthcare provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Side Effects

Side effects may include headaches, insomnia, sleep disturbances, irritability and mood changes.

Contraindications

There are no known contraindications.

Product Interactions

Insulin: Theoretically, comcomitant use might increase the risk of hypoglycaemia.

Levothyroxine: Chromium is believed to bind levothyroxine in the intestinal tract and may lead to reduced absorption. Take levothyroxine at least 30-minutes before or 3-4 hours after chromium.

Medicines that deplete chromium levels or affect absorption include:

• Antacids

• Corticosteroids

• H2-Blockers

• Proton Pump Inhibitors (PPIs)

Special Precautions

Use cautiously in individuals with renal or hepatic insufficiency.

Use cautiously in individuals with diabetes or in individuals receiving oral hypoglycemics or insulin. Blood glucose should be closely monitored and the dosage of diabetic agents may need to be reduced. This should be carefully coordinated under the supervision of a health care provider.

Pregnancy & Breastfeeding

Chromium should only be used in pregnancy under the supervision of a medical practitioner. Breastfeeding women should not take more than 1 tablet per day, unless under the supervision of a medical practitioner.

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